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  • 标题:Plasma Fatty Acids in Zambian Adults with HIV/AIDS: Relation to Dietary Intake and Cardiovascular Risk Factors
  • 本地全文:下载
  • 作者:Christopher K. Nyirenda ; Edmond K. Kabagambe ; John R. Koethe
  • 期刊名称:Journal of Nutrition and Metabolism
  • 印刷版ISSN:2090-0724
  • 电子版ISSN:2090-0732
  • 出版年度:2015
  • 卷号:2015
  • DOI:10.1155/2015/635817
  • 出版社:Hindawi Publishing Corporation
  • 摘要:Objective. To determine whether 24 hr dietary recalls (DR) are a good measure of polyunsaturated fatty acid (PUFA) intake when compared to plasma levels, and whether plasma PUFA is associated with markers of HIV/AIDS progression and cardiovascular disease (CVD) risk. Methods. In a cross-sectional study among 210 antiretroviral therapy-naïve HIV-infected adults from Lusaka, Zambia, we collected data on medical history and dietary intake using 24 hr DR. We measured fatty acids and markers of AIDS progression and CVD risk in fasting plasma collected at baseline. Results. PUFA intakes showed modest correlations with corresponding plasma levels; Spearman correlations were 0.36 for eicosapentaenoic acid and 0.21 for docosahexaenoic acid. While there were no significant associations between total plasma PUFA and C-reactive protein (CRP) or lipid levels, plasma arachidonic acid was inversely associated with CRP and triglycerides and positively associated with HDL-C, CD4
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