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  • 标题:DOLUTEGRAVIR efficacy in HIV infected patients
  • 作者:Irina Magdalena Dumitru ; Roxana Carmen Cernat ; S. Rugină
  • 期刊名称:ARS Medica Tomitana
  • 电子版ISSN:1841-4036
  • 出版年度:2015
  • 卷号:21
  • 期号:1
  • 页码:42-51
  • DOI:10.1515/arsm-2015-0019
  • 语种:English
  • 出版社:Walter de Gruyter GmbH
  • 摘要:In the past years there have been numerous discoveries regarding treatment of patients with HIV. If at first the doctors watched as patients live longer, now we want these patients to live better with regimens potent, safe, individualized and without side effects. HAART has revolutionized “the world HIV” and caused a significant reduction in mortality, and morbidity associated with HIV-related opportunistic infections. However, side effects associated with HAART, metabolic toxicity (such as abnormal fat distribution, abnormal lipid and glucose metabolism, and bone loss) and the large number of pills led to decreased patient adherence.
  • 关键词:Dolutegravir ; HAART ; efficacy ; resistance ; safety
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