Component part of the Carpathian-Danubian-Pontic space, the interfluve area between Prut and Dniester is subject to the regional process of climate evolution and change. In what regards the concept of human-influenced pedogenesis, the role of the biological factor is significantly reduced. As a consequence the direction and intensity of the elementary landscape and pedogenetic processes are determined by the relations between climate and the geomorphological factor. In the conditions of a relative stability of the geomorphological factor, the determining role is held by climate. To this is added soil vulnerability to the implications of climate changes, determined by the degree of soil physical degradation but also by a series of intrinsic and external (drainage) factors. This implies the idea of the control and management of the landscape and pedogenetic implications of climate changes by improving soil physical characteristics.