摘要:A complete fingerprint of a tissue sample requires a detailed description of its cellular and extracellular components while minimizing artifacts. We introduce the application of a novel scanning electron microscope ( airSEM TM) in conjunction with light microscopy for functional analysis of tissue preparations at nanometric resolution ( airSEM TM and a light microscope on the same platform, provides a convenient and easy-to-use system for obtaining structural and functional correlative data. The airSEM TM imaging station complements other existing imaging solutions and shows great potential for studies of complex biological systems.