期刊名称：Revista Internacional de Contaminación Ambiental
印刷版ISSN：0188-4999
出版年度：1989
卷号：5
期号：1
页码：41-48
出版社：Centro de Ciencias de la Atmósfera
摘要：Several concentrations of methyl, ethyl and butyl cellosolves were applied to cultures of human lymphocytes in order to investigate their effect in the induction of chromosomal aberrations and sister chromatid exchanges. When metaphase cells were observed, it was noted that these solvents did not increase significantly the frequency of aberrations, but they did make a difference in the case of sister chromatid exchanges. The effectiveness order was: ethyl> butyl> methyl. Ethyl cellosolve was the most toxic because 2000 ppm inhibited the cell division, which did not happen with the other two cellosolves.
其他摘要：Several concentrations of methyl, ethyl and butyl cellosolves were applied to cultures of human lymphocytes in order to investigate their effect in the induction of chromosomal aberrations and sister chromatid exchanges. When metaphase cells were observed, it was noted that these solvents did not increase significantly the frequency of aberrations, but they did make a difference in the case of sister chromatid exchanges. The effectiveness order was: ethyl> butyl> methyl. Ethyl cellosolve was the most toxic because 2000 ppm inhibited the cell division, which did not happen with the other two cellosolves.
