期刊名称：Revista Internacional de Contaminación Ambiental
印刷版ISSN：0188-4999
出版年度：1997
卷号：13
期号：1
页码：15-21
语种：Spanish
出版社：Centro de Ciencias de la Atmósfera
摘要：Different concentrations of two petrol commercial samples, leaded and unleaded, were evaluated for genotoxicity in human peripheral blood lymphocyte cultures. Sister-chromatid exchanges (SCE) and micronuclei (MN) were scored as genetic endpoints to measure the genotoxicity of the samples in cultures set up from three different healthy donors. The treatment of the cell culture was done employing different petrol concentrations (from 0.019 to 0.312 µl/ml). From our results we can conclude that both petrol samples induced a slight but concentration-dependent increase in the frequency of SCE, while no increase was detected in the MN frequency.
其他摘要：Different concentrations of two petrol commercial samples, leaded and unleaded, were evaluated for genotoxicity in human peripheral blood lymphocyte cultures. Sister-chromatid exchanges (SCE) and micronuclei (MN) were scored as genetic endpoints to measure the genotoxicity of the samples in cultures set up from three different healthy donors. The treatment of the cell culture was done employing different petrol concentrations (from 0.019 to 0.312 µl/ml). From our results we can conclude that both petrol samples induced a slight but concentration-dependent increase in the frequency of SCE, while no increase was detected in the MN frequency.
关键词：petrol; human lymphocyte cultures; micronuclei; sister-chromatid exchanges;petrol; human lymphocyte cultures; micronuclei; sister-chromatid exchanges
其他关键词：petrol; human lymphocyte cultures; micronuclei; sister-chromatid exchanges
