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  • 标题:Ranking the impact of human health disorders on gut metabolism: Systemic lupus erythematosus and obesity as study cases
  • 本地全文:下载
  • 作者:David Rojo ; Arancha Hevia ; Rafael Bargiela
  • 期刊名称:Scientific Reports
  • 电子版ISSN:2045-2322
  • 出版年度:2015
  • 卷号:5
  • DOI:10.1038/srep08310
  • 出版社:Springer Nature
  • 摘要:Multiple factors have been shown to alter intestinal microbial diversity. It remains to be seen, however, how multiple collective pressures impact the activity in the gut environment and which, if any, is positioned as a dominant driving factor determining the final metabolic outcomes. Here, we describe the results of a metabolome-wide scan of gut microbiota in 18 subjects with systemic lupus erythematosus (SLE) and 17 healthy control subjects and demonstrate a statistically significant difference ( p p
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