Recent advances in organ transplantation have promised certain benefits to humankind. Consequently, it is necessary to take into consideration all aspects of these new approaches and provide specific ethical guidelines for research in this field. Considering the ever-increasing advancements of transplantation in Iran and noting the necessity of scientific researches in this field, and to observe ethical principles in such researches, compilation of the "National Ethical Guidelines for Transplantation Researches", as one topic of the "Specific National Ethical Guidelines for Biomedical Research" were considered in our country. We stated some points of this guideline in this article.