Rodents are one of the main health problems in the cities, especially in coastal area. These animals make economic damages and are potential health dangers in Bandar Abbas, the main economic southern port of Iran . In this study, rodents were captured from different parts of the city, before and after a control program during 2003-2004, transferred to the laboratory, identified and examined for ecto-parasites. Totally 105 rodents demonstrating four species: Rattus rattus (3%), R. norvegicus (78%), Mus musculus (3%) and Tatera indica (16%), were captured before the control program. The most frequency was observed in Ayatollah Ghafari quarter, 10 rodents per 24 traps. After 12 months, the duration of control program, rodents were re-captured to assessment the success of control activity. In this stage 35 small mammals demonstrated four species were obtained: R.norvegicus (51.4%), R.rattus (37.1%), T.indica (8.6%) and one weasel (2.9%). We found the most frequency in Khoon-sorkh quarter with 6 rodents per 24 traps. The identified ectoparasites were Xenopsylla buxtoni, Rhipicephalus sp., Polyplax gerbilli, Haplopleura captiosa, Ornithonyssus bacoti, Laelaps nuttalli, Dermanyssus americanus, Dermanyssus sanguineus, Haemolaelaps glasgowi and Echinolaelaps echidninus. The number of rodents reduced to one third after control program, shows the relative success of this program (p<0.05).