Atrazine, a herbicide widely used in corn production, is frequently detected as pesticide in water resources. In this research, four agricultural fields with a long history of atrazine application in Shiraz and its vicinity in Fars province of Iran, have been studied to determine the fate of atrazine through the passage of time. These four farms were cultivated under a crop rotation (corn-wheat) during the past 10 years. Samples were collected from four soil profiles of 0-10, 10-20, 20-40, and 40-60 cm soil depth at different times. The time intervals for soil sampling started before atrazine application and continued until no atrazine was detected. According to the general linear model, there was no significant difference between atrazine residual concentrations and the soil moisture and depth (p ³ 0.05). But, significant difference between atrazine residual concentrations and the sampling regions was observed (p<0.001). Based on the data, atrazine leaching and dissipation rate in different soil profiles in the four sampling regions were high and significant. Therefore, there is a high risk of atrazine pollution in groundwater resources of the region.