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  • 标题:STUDY OF SOME BIOLOGICAL ACTIVE COMPOUNDS AND SYNTHESIS OF 1-{[(-1-AZA-2-ARYL VINYL)AMINO] THIOXOMETHYL} - 4 - [(4-CHLORO PHENYL) METHYLENE] -2- PHENYL-2-IMIDAZOLIN -5-ONES
  • 本地全文:下载
  • 作者:Dr. Prakash Vaghela
  • 期刊名称:SCHOLARLY RESEARCH JOURNAL FOR INTERDISCIPLINARY STUDIES
  • 印刷版ISSN:2319-4766
  • 电子版ISSN:2278-8808
  • 出版年度:2015
  • 期号:4239
  • 页码:3109 – 3113
  • 出版社:SCHOLARLY RESEARCH JOURNAL'S
  • 摘要:4-[(4-chloro phenyl) methylene]-2-phenyl-1,3-oxazolin-5-one and thiosemicarbazide were mixed in a round bottom flask. Pyrindine was added to the mixture and refluxed on heating mental for 3 hours. Content colled, then poured over crushed ice and recrystalised from alchohol. Product (II) obtained. 1-(hydrazinothioxomethyl)-4-[(4-chloro phenyl) methylene]-2-phenyle-2-imidazolin-5-one and benzaldehyde were refuxed in ethanol containing a few drops of gl. Acetic acid for 3 hours in water bath. Then excess of solvent was distilled off and crude product was washed with water, filled, dried and further washed with petroleium ether. Recrystallied product(III) from R.F.Spirit. The other 15 compounds were prepared by following the above procedure. The structure of these compounds were established on the basis of analytical data, 1HNMR, IR and mass spectral studies. All the newly synthesized compounds were evaluated for their anti-micribial activities
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