摘要:ABSTRACT In most sensitive occupations such as nuclear, military and chemical industries closed circuit systems and visual display terminals (VDTs) are used to carefully control and assess sensitive processes. Visual fatigue is one of the factors decreasing accuracy and concentration in operators causing faulty perception. This study aimed to find out a relationship between visual fatigue symptoms (VFS) of Flicker value variations in video display terminal (VDT) operators. This cross-sectional study, conducted in 2011, aimed to examine visual fatigue and determine the relationship between its symptoms and visual flicker value changes in 248 operators of VDTs in several occupations. The materials used in this study were a visual fatigue questionnaire of VDTs and a VFM-90.1 device. Visual fatigue was measured in two stages (prior to beginning to work and 60 min later). The data were analyzed by SPSS11.5, using descriptive statistics, paired t-test, simple and multiple linear regressions, correlation and recognition coefficients. Then regression equations of changes in flicker value depending on the changes in the main domains and the changes in final score before the questionnaire were obtained. Paired t-test indicated significant differences in the mean score of visual fatigue symptoms and the mean score of flicker value between the two stages, respectively (P ≤ 0.001). Simple and multiple regressions of flicker value variations, for the last visual fatigue changes in questionnaire score and the four main domains of the questionnaire were obtained R2 = 0.851 and R2 = 0.853, respectively. Correlation coefficient in the above tests indicated reverse and significant relationships among flicker value changes with changes in questionnaire score and visual fatigue symptoms. Diagnosing the first symptoms of visual fatigue could be an appropriate warning for VDTs operators in sensitive occupations to react suitably, in behavior and management, to control or treat visual fatigue and prevent errors efficiently.