摘要:The MKK3-p38 MAPK pathway has been reported to mediate larval settlement in Amphibalanus (= Balanus ) amphitrite . To clarify the underlying molecular mechanism, we applied label-free proteomics to analyze changes in the proteome of cyprids treated with a p38 MAPK inhibitor. The results showed that the expression levels of 80 proteins were significantly modified ( p A. amphitrite cyprids, including the energy supply, metamorphosis, neural system and cement glands.