期刊名称：Journal of Emerging Trends in Computing and Information Sciences
电子版ISSN：2079-8407
出版年度：2012
卷号：3
期号：6
页码：885-895
出版社：ARPN Publishers
摘要：Hepatitis C is a predominant genotype found throughout the Middle East and parts of Africa, with high population prevalence in Egypt. Due to the world’s constant effort to find treatment for this fatal disease; many researches and trials have been made. It has become evident that virus C itself envelopes a self destructive gene [1], which if activated by a specific order to the mRNA aboard the virus, forms interferon. Interferon is an anti-viral if produced from virus C itself becomes specific only to it. Through a variety of bioinformatics tools we architect algorithms to enhance the chance of finding this gene which order the mRNA to produce the virus C specific interferon .Tools such as RNA to protein synthesis, gene prediction, protein classification and gene classification have been constructed and tried to reach this goal .As a result of these trials, several matches were made with alternating percentages but at least acknowledging the possibility this interferon/RNA analysis.
关键词：Virus C type 4; Interferon; RNA; DNA; Hidden Markov Models
