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  • 标题:Polyunsaturated Fatty Acid Composition of Maternal Diet and Erythrocyte Phospholipid Status in Chilean Pregnant Women
  • 本地全文:下载
  • 作者:Karla A. Bascuñán ; Rodrigo Valenzuela
  • 期刊名称:Nutrients
  • 电子版ISSN:2072-6643
  • 出版年度:2014
  • 卷号:6
  • 期号:11
  • 页码:4918-4934
  • DOI:10.3390/nu6114918
  • 语种:English
  • 出版社:MDPI Publishing
  • 摘要:Chilean diets are characterized by a low supply of n-3 polyunsaturated fatty acids (n-3 PUFA), which are critical nutrients during pregnancy and lactation, because of their role in brain and visual development. DHA is the most relevant n-3 PUFA in this period. We evaluated the dietary n-3 PUFA intake and erythrocyte phospholipids n-3 PUFA in Chilean pregnant women. Eighty healthy pregnant women (20–36 years old) in the 3rd–6th month of pregnancy were included in the study. Dietary assessment was done applying a food frequency questionnaire, and data were analyzed through the Food Processor SQL® software. Fatty acids of erythrocyte phospholipids were assessed by gas-liquid chromatography. Diet composition was high in saturated fat, low in mono- and PUFA, high in n-6 PUFA (linoleic acid) and low in n-3 PUFA (alpha-linolenic acid and DHA), with imbalance in the n-6/n-3 PUFA ratio. Similar results were observed for fatty acids from erythrocyte phospholipids. The sample of Chilean pregnant women showed high consumption of saturated fat and low consumption of n-3 PUFA, which is reflected in the low DHA content of erythrocyte phospholipids. Imbalance between n-6/n-3 PUFA could negatively affect fetal development. New strategies are necessary to improve n-3 PUFA intake throughout pregnancy and breast feeding periods. Furthermore, it is necessary to develop dietary interventions to improve the quality of consumed foods with particular emphasis on n-3 PUFA.
  • 关键词:pregnancy; dietary intake; n -6 and n -3 PUFA intake; DHA; fatty acid phospholipids pregnancy ; dietary intake ; n -6 and n -3 PUFA intake ; DHA ; fatty acid phospholipids
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