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  • 标题:From Lab to Pharmacy Shelves: The Story of a Plant Derived Anticancer Drug, "Paclitaxel"
  • 本地全文:下载
  • 作者:Junjua, Maira ; Jafar, Sana ; Karamat, Fazeelat
  • 期刊名称:Journal of Bioresource Management
  • 印刷版ISSN:2309-3854
  • 出版年度:2015
  • 卷号:2
  • 期号:4
  • 页码:4
  • 出版社:Wright State University
  • 摘要:Paclitaxel (Taxol®) is a highly praised anticancer drug, known for its efficiency in treating different cancers. It belongs to a class of compounds called taxanes that are derived from the plants of the genus Taxus. This drug is now FDA approved, but there was a time when the name Taxol was less known to the scientific world. Taxol, being a unique molecule in its structure, properties and mechanism of action, has undergone more than 30 years of trials, and faced a lot of hurdles to leave the bench of a laboratory and reach the shelves of a pharmacy. This review focuses on the story of Taxol, how it began and how it achieved the status of Paclitaxel.
  • 关键词:Secondary Metabolites; Taxus brevifolia; Taxol; Paclitaxel
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