摘要：The advent of the OMIC technologies has strongly evolved the knowledge about the origin, the type and the response to therapy of a given tumor. To date we are aware that the epigenetic and genomic landscapes of tumors which origin, histopathological diagnoses and clinical stages are almost identical can be highly heterogeneous. Initially, the Human Genome Project represented the reference map for the human genome and provided the ideal background for the development of technology and analytic tools to decipher and rationalize enormous quantities of genomic data [1].
