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  • 标题:The relationship between long-term changes in plasma B-type natriuretic peptide levels and electrocardiographic findings
  • 本地全文:下载
  • 作者:Shinji Fukazawa ; Koji Teruya ; Takamoto Uemura
  • 期刊名称:Environmental Health and Preventive Medicine
  • 印刷版ISSN:1342-078X
  • 电子版ISSN:1347-4715
  • 出版年度:2008
  • 卷号:13
  • 期号:3
  • 页码:156-161
  • DOI:10.1007/s12199-008-0027-z
  • 语种:English
  • 出版社:Springer Japan
  • 摘要:Objectives

    Changes in B-type natriuretic peptide (BNP) and electrocardiographic (ECG) findings in an adult Japanese population were measured over a 5-year period, and the statistical relationships between these were evaluated.

    Methods

    This was a longitudinal analysis in which data were collected on 353 subjects (135 men and 218 women) who had undergone general health checks in 1998 and 2003.

    Results

    Data were examined by correlation coefficient and one-way analysis of covariance using repeated measurements. The correlation coefficient for BNP between 1998 and 2003 was 0.622 ( P P P P Conclusions

    This regional longitudinal study revealed a gender difference in the relationship between long-term changes in BNP and ECG findings, suggesting that a 10 pg/ml or more increase in BNP in men over a 5-year period may a indicate worsening of cardiac function and the need for intervention.

  • 关键词:BNP ;ECG ;Long-term change
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