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  • 标题:HPLC analysis of potentially harmful substances released from dental filing aterials available on the EU market
  • 本地全文:下载
  • 作者:Konrad Małkiewicz ; Alfred Owoc ; Mariusz Kluska
  • 期刊名称:Annals of Agricultural and Environmental Medicine
  • 印刷版ISSN:1232-1966
  • 电子版ISSN:1898-2263
  • 出版年度:2014
  • 卷号:21
  • 期号:1
  • 页码:86-90
  • 出版社:Institute of Agricultural Medicine in Lublin
  • 摘要:Introduction. Incomplete cross-linking of composite dental materials leads to their susceptibility to degradation in theenvironment of non-organic and organic solvents, contributing to the release of chemical compounds which are potentiallyharmful to living organisms.Objective. The aim of the study was an evaluation in in vitro conditions of releasing of potentially toxic substances fromsix dental composite materials available in EU countries.Materials and methods. The following compounds released from the samples stored in water were analyzed: bisphenolA (BPA), triethylene glycol-dimethacrylate (TEGDMA), urethane dimethacrylate (UDMA) and ethylene glycol dimethacrylate(EDGMA). Analysis of the substances was performed with the use of high performance liquid chromatography, after thefollowing incubation periods: 1 hour, 24 hours, 7 days and 30 days.Results. Among the analyzed substances, after 1 hour of incubation, the highest average concentration was found forTEGDMA – 2045 μg cm-3 (in Herculite XRV material), after 24 hours – for UDMA 4.402 μg cm-3 (in Gradia Direct Anteriormaterial) and after 7 and 30 days for TEGDMA: 8.112 and 6.458 μg·cm-3 respectively (in Charisma material).Conclusions. The examined composites used for reconstruction of hard tissues of teeth remain chemically unstable afterpolymerization, and release potentially harmful substances in conditions of the present study. The dynamics of the releasingof potentially harmful substances is correlated with the period of sample storage in water
  • 关键词:Dental composite; bisphenol A (BPA); high performance liquid chromatography (HPLC)
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