期刊名称：Annals of Agricultural and Environmental Medicine
印刷版ISSN：1232-1966
电子版ISSN：1898-2263
出版年度：2014
卷号：21
期号：3
页码：576-580
DOI：10.5604/12321966.1120605
出版社：Institute of Agricultural Medicine in Lublin
摘要：Introduction. Oxygen is an essential element for sustaining the life of aerobes; however, in certain conditions it may betoxic for these organisms. This is due to so-called reactive oxygen species – ROS. Factors which cause the production offree radicals include ionizing radiation, UV radiation, high temperature, and hazardous substances, such as phenols, carbonmonoxide, e.g. in smokers, also air pollution and drugs.Objective. The objective of the study was analysis of the total antioxidant status (TAS) in stimulated and unstimulatedsaliva, according to the number of active carious lesions in generally healthy non-smokers aged 15–17.Materials and method. The study covered 113 adolescents aged 15–17 in whom the state of dentition was evaluated usingthe DMFT (Decayed-Missing-Filled) index, and oral hygiene assessed based on the OHI-S (Oral Hygiene Index-Simplified)index. TAS in saliva was determined by means of a Randox Labolatories Ltd. test kit, by the spectrophotometric method.Results. Based on the results of the study, it was found that in the population examined an increase in the number of cariouslesions was accompanied by a significant decrease in the TAS, both in stimulated and unstimulated saliva.Conclusions. A health-promoting life style, maintenance of basic principles of oral hygiene and care of general healththrough the elimination of harmful habits decrease the risk of dental caries.
关键词：dental caries; reactive oxygen species; oxidative stress; TAS; environment of the oral cavity
