期刊名称：Annals of Agricultural and Environmental Medicine
印刷版ISSN：1232-1966
电子版ISSN：1898-2263
出版年度：2015
卷号：22
期号：1
页码：172-177
DOI：10.5604/12321966.1141390
出版社：Institute of Agricultural Medicine in Lublin
摘要：Introduction. Treatment with fixed orthodontic appliances requires the application of adhesive systems to enable securefastening of brackets and retainers to the surface of tooth enamel. The orthodontic bonding systems are similar in terms ofchemical composition to dental filling materials, the chemical stability of which is not satisfactory. Particularly alarming isthe release of bisphenol A and its derivatives to the external environment, which has been well-documented for materialsused in conservative dentistry.Objectives. The aim of the study was an in vitro assessment of the release of biologically harmful bisphenol A and itsderivatives from orthodontic adhesives available on the European market, as a potential health risk factor for orthodonticpatients.Material and methods. The study assessed levels of BPA, BPA polymers and Bis-GMA resin in eluates of six commonly usedorthodontic adhesives: Light Bond, Transbond XT, Resilence, Aspire, GrĕnGloo and ConTec LC, obtained after one hour, 24hours, 7 days and 31 days of material sample storage in water. The presence and concentration of the studied chemicals inthe obtained solutions were identified using the HPLC method.Results. The highest (p≤0.05) concentration of BPA at 32.10μg/ml was observed in the Resilence material eluates. The highestconcentration of poly-bisphenol A was found in solutions obtained after incubation of ConTec LC adhesive at 371.90μg/ml,whereas the highest amount of Bis-GMA resin (425.07μg/ml) was present in Aspire material eluates.Conclusions. 1) In conditions of the current experiment it was demonstrated that most of the assessed orthodontic adhesiveresins available on the European market and released into the outside environment – biologically harmful bisphenol A orits derivatives, posing a potential threat to the patients’ health. 2) Release of BPA and its derivatives into aqueous solutionsis the highest in the early stages of sample incubation
关键词：bisphenol A; orthodontic adhesives; HPLC; health risk factors
