期刊名称：Annals of Agricultural and Environmental Medicine
印刷版ISSN：1232-1966
电子版ISSN：1898-2263
出版年度：2015
卷号：22
期号：2
页码：362-367
DOI：10.5604/12321966.1152096
出版社：Institute of Agricultural Medicine in Lublin
摘要：Objective. Although trace elements are regarded crucial and their content has been determined in number of tissue thereare only few papers addressing this problem in intervertebral disc in humans. Most of the trace elements are importantsubstrates of enzymes influencing metabolism and senescence process. Others are markers of environmental pollution.Therefore the aim of the research was to analyzed of the trace element content in the intervertebral disc, which may bea vital argument recognizing the background of degenerative changes to be the effect of the environment or metabolicfactors.Materials and methods. Material consist of 18 intervertebral disc from 15 patients, acquired in surgical procedure of due tothe degenerative disease with Atomic Absorption Spectrometry content of Al, Cd, Co, Pb, Cu, Ni, Mo, Mg, Zn was evaluated.Results. Only 4 of the trace elements were detected in all samples. The correlation analysis showed significant positiveage correlation with Al and negative in case of Co. Among elements significant positive correlation was observed betweenAl/Pb, Co/Mo, Al/Mg, Al/Zn Pb/Zn and Mg/Zn. Negative correlation was observed in Al/Co, Cd/Mg, Co/Mg, Mo/Mg, Co/Znand Mo/Zn.Conclusions. This study is the first to our knowledge that profiles the elements in intervertebral disc in patients withdegenerative changes. We have confirmed significant differences between the trace element contents in intervertebraldisc and other tissue. It can be ground for further investigation
