期刊名称：Annals of Agricultural and Environmental Medicine
印刷版ISSN：1232-1966
电子版ISSN：1898-2263
出版年度：2015
卷号：22
期号：3
页码：409-411
DOI：10.5604/12321966.1167702
出版社：Institute of Agricultural Medicine in Lublin
摘要：Introduction and objectives. Human granulocytic anaplasmosis (HGA) is an emerging tick-borne infectious disease causedby Anaplasma phagocytophilum. In Europe, the first serological evidence of HGA was described in 1995 in Switzerland, and thefirst clinical case was confirmed in 1997 in Slovenia. Since then, many European countries, including Slovakia, have reportedthe occurrence of HGA. The aim of this study was to examine the occurrence of IgG antibodies against A. phagocytophilumin blood sera of humans with suspected tick-borne encephalitis.Material and methods. 181 people were examined for the presence of anti-A. phagocytophilum IgG antibodies; 113 werepatients with suspected TBE (65 males, 48 females), and 68 from the control group (18 males, 50 females). Respondents wereaged 2–80 years (mean age: 31.39; STD: 17.1). Anti-A. phagocytophilum IgG antibodies were detected by the IFA IgG test.Relative risk (RR) and their 95% confidence intervals (95% CI) were estimated for the occurrence of IgG A. phagocytophilumantibodies.Results. Of the total number of 181 people examined, 32 (17.7%) showed positive for IgG antibodies against A. phagocytophilum,22 of whom were patients with suspected TBE (19.5%) and 10 people from control group (14.7%). The RR of occurrence ofIgG A. phagocytophilum was 1.3-times higher in the patients with suspected TBE than in the control group.Conclusion. None of the examined patients with suspected TBE had the disease confirmed. Hoever, as shown by the results,the relative risk of occurrence of anaplasmosis is higher in people examined for some another vector-borne disease (in thiscase TBE). Therefore, the performance of screening examinations in patients suspected of having any tick-borne diseaseis very important
关键词：Anaplasma phagocytophilum; human granulocytic anaplasmosis; Ixodes ricinus; tick-borne encephalitis; Slovakia
