期刊名称：Annals of Agricultural and Environmental Medicine
印刷版ISSN：1232-1966
电子版ISSN：1898-2263
出版年度：2015
卷号：22
期号：3
页码：414-417
DOI：10.5604/12321966.1167704
出版社：Institute of Agricultural Medicine in Lublin
摘要：The article focuses on the clinical and laboratory diagnosis of human granulocytic anaplasmosis (HGA) caused by Anaplasmaphagocytophilum infection in one of 28 patients (3.6%; n=1/28 tested samples) with early Lyme borreliosis. The clinical andlaboratory results of a 42-year-old patient fulfilled criteria of confirm anaplasmosis and suggest an acute stage of illness. Thedescribed case provides strong presumptive evidence that infection in this patient was acquired with a pathogenic strainof A. phagocytophilum through a tick bite. A positive DNA with PCR for A. phagocytophilum infection was sequenced andanalyzed phylogenetically. Physicians should consider the possibility of anaplasmosis in patients with early Lyme borreliosis,and A. phagocytophilum should be considered as a differential diagnosis in all patients from an endemic region of potentialhigh risk factors for tick-borne diseases
关键词：Anaplasma phagocytophilum; anaplasmosis; coinfection; Lyme borreliosis; clinical and molecular diagnosis
