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  • 标题:Can selection explain the protective effects of farming on asthma?
  • 本地全文:下载
  • 作者:Wijnand Eduard ; Vivi Schlünssen ; Torben Sigsgaard
  • 期刊名称:Annals of Agricultural and Environmental Medicine
  • 印刷版ISSN:1232-1966
  • 电子版ISSN:1898-2263
  • 出版年度:2015
  • 卷号:22
  • 期号:3
  • 页码:467-469
  • DOI:10.5604/12321966.1167715
  • 出版社:Institute of Agricultural Medicine in Lublin
  • 摘要:Introduction and objective. Reduced asthma and allergy risks in farmers have been ascribed to microbial exposures.However, selection may also play a role and this was assessed in two Scandinavian farming populations.Materials and methods. Asthma prevalence in 739 Danish farming students was compared to that of 1,105 siblings. 8,482Norwegian farmers were also compared with 349 early retired farmers.Results. The prevalence of ever-asthma was 5.4% in farming students and 5.2% in siblings (OR 1.1; 95%CI 0.73–1.7). Currentasthma in farmers was 3.0% compared to 6.3% in farmers who had retired early (OR 1.8, 95%CI 1.1–2.9). Adjustments forearly retirement increased the asthma prevalence by 0.3–0.6%. Farmers who had changed production were more likely tohave asthma (OR 9.8, 95% CI 6.0–16).Conclusions. No healthy worker selection into farming was observed and changes in asthma prevalence due to earlyretirement were small. Selection effects are therefore unlikely to explain the protective effects of farming on asthma
  • 关键词:Farmers; farming students; healthy worker selection; survivor selection; cross-sectional study
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