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  • 标题:Immunological parameters as a new lead in the diagnosis of ovarian cancer
  • 本地全文:下载
  • 作者:T. BAERT ; D. TIMMERMAN ; I. VERGOTE
  • 期刊名称:Facts, Views & Vision in ObGyn
  • 印刷版ISSN:2032-0418
  • 出版年度:2015
  • 卷号:7
  • 期号:1
  • 页码:67-72
  • 出版社:Universa Press
  • 摘要:Ovarian cancer is the leading cause of pelvic gynecological cancer death in Europe. Prognosis is poor in women diagnosed at stage III to IV or in case disease recurs. Platin-based chemotherapy and radical surgery have already improved prognosis significantly. Novel strategies in the treatment of ovarian cancer are being searched for. The study of the immune system as a valuable parameter in the development of ovarian cancer has been neglected for a long time. Nevertheless, this is a field in full progression and might open new perspectives in the diagnosis and prognosis of ovarian cancer patients and could lead to a more motivated choice of targeted therapies.
  • 关键词:Ovarian cancer; diagnosis; prognostic marker; immunosuppression; regulatory T cell; myeloid derived;suppressor cells; tumor-associated macrophages.
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