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  • 标题:Gastric Intestinal Metaplasia: Prevalence, Clinical Presentation, Endoscopic and Histological Features
  • 作者:Silvia Cosmina Drasovean ; Diana Elena Morărașu ; Ofelia Daniela Pascarenco
  • 期刊名称:Acta Medica Marisiensis
  • 电子版ISSN:2247-6113
  • 出版年度:2016
  • 卷号:62
  • 期号:1
  • 页码:56-59
  • DOI:10.1515/amma-2015-0061
  • 语种:English
  • 出版社:Walter de Gruyter GmbH
  • 摘要:Background and Aim: Gastric intestinal metaplasia represents a risk factor for intestinal type of gastric cancer. Gastric intestinal metaplasia seems to be associated with Helicobacter pilory infection in relatives of patients with gastric cancer. The aim of this study was to determine the prevalence, clinical, endoscopic and histological features of gastric intestinal metaplasia. Material and Methods: We retrospectively analyzed the esophagogastroduodenoscopies with biopsies performed between January 1, 2014 and October 31, 2014. Collected and analyzed data included age, gender, symptoms, endoscopic and histological findings. Results: Four hundred eighty-two patients were included in the study. One hundred thirty-seven patients had gastric intestinal metaplasia, which presented a prevalence was 28,4%. A similar distribution between gender was observed with a significant increase of gastric intestinal metaplasia with age (p=0,0001). Regarding the indication for endoscopy, the prevalence of gastric intestinal metaplasia was: 17 % among patients with dyspeptic syndrome, 2 % in patients with anemia and 5 % in patients examined for other symptoms. Endoscopic findings showed gastric intestinal metaplasia was significantly associated with atrophic gastritis (p=0.0001), erythematous gastritis (p=0.0079), while there was no association with erosive gastritis (p=0.24) and peptic ulcer (p=0.19). Conclusions: Gastric intestinal metaplasia is frequently recorded in patients undergoing in esophagogastroduodenoscopies with associated biopsies. Endoscopic findings like erythema and atrophy is strongly associated with gastric intestinal metaplasia emphasizing the importance of sampling biopsies.
  • 关键词:Helicobacter pylori ; gastric intestinal metaplasia ; gastric cancer
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