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  • 标题:Graham Little-Lassueur Syndrome with Hypertrophic Lichen Planus in a Patient with Chronic Hepatitis C
  • 作者:Mihail Alexandru Badea ; Florin Buicu ; Anton Mihai Ţilea
  • 期刊名称:Acta Medica Marisiensis
  • 电子版ISSN:2247-6113
  • 出版年度:2016
  • 卷号:62
  • 期号:1
  • 页码:149-151
  • DOI:10.1515/amma-2015-0089
  • 语种:English
  • 出版社:Walter de Gruyter GmbH
  • 摘要:Graham Little-Lassueur Syndrome (GLLS) is considered a form of lichen planopilaris which associates follicular lichen planus, cicatricial alopecia of the scalp and noncicatricial alopecia of the axillary and/or pubic regions. We present the case of a 47 years old female patient, known for 5 years with chronic hepatitis C and a poor therapeutic control of the disease due to Interferon intolerance. She presented to our clinic for the occurrence on the shins of some well-defined, intensely pruritic erythematous plaques, covered with thick scales, with a verrucous appearance, accompanied by excoriations. The skin biopsy reveal hypertrophic lichen planus on the shins and lichen planopilaris on the scalp. The patient was treated with systemic antihystamines, topical corticosteroids and salicylic acid under occlusion, emollients, phototherapy UVB narrow band 4 sessions/week for 3 weeks, cryotherapy. From our knowledge this is the first case of GLLS associated with chronic viral hepatis C.
  • 关键词:Graham Little Lassueur syndrome ; hypertrophic lichen planus ; chronic hepatitis C
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