出版社:Japan Science and Technology Information Aggregator, Electronic
摘要:We attempted to evaluate differences in intoxication in mice after the administration of various alcoholic beverages. Measurements of locomotor activity and elevated plus-maze test in mice did not show differences in the extent of intoxication after oral administration of alcoholic beverages (sake, red wine, shochu, and whiskey; approximately 15% alcohol, 1.2g of alcohol/kg BW dosed single or twice). Changes in the concentrations of ethanol and acetaldehyde in blood and brain were very similar 0.5, 3, and 5 hours after the oral administration of alcoholic beverages (sake and shochu; 15% alcohol, 2.4g of alcohol/kg BW). There seems to be no differences in intoxication in mice after the administration of alcoholic beverages at the same doses with the same alcohol content.