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  • 标题:Behavioral Evaluation of Intoxication in Mice by Oral Administration of Alcoholic Beverages
  • 本地全文:下载
  • 作者:Hanae IZU ; Kuniyasu GOTO
  • 期刊名称:日本醸造協会誌
  • 印刷版ISSN:0914-7314
  • 电子版ISSN:2186-4012
  • 出版年度:2009
  • 卷号:104
  • 期号:10
  • 页码:787-795
  • DOI:10.6013/jbrewsocjapan.104.787
  • 出版社:Japan Science and Technology Information Aggregator, Electronic
  • 摘要:We attempted to evaluate differences in intoxication in mice after the administration of various alcoholic beverages. Measurements of locomotor activity and elevated plus-maze test in mice did not show differences in the extent of intoxication after oral administration of alcoholic beverages (sake, red wine, shochu, and whiskey; approximately 15% alcohol, 1.2g of alcohol/kg BW dosed single or twice). Changes in the concentrations of ethanol and acetaldehyde in blood and brain were very similar 0.5, 3, and 5 hours after the oral administration of alcoholic beverages (sake and shochu; 15% alcohol, 2.4g of alcohol/kg BW). There seems to be no differences in intoxication in mice after the administration of alcoholic beverages at the same doses with the same alcohol content.
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