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  • 标题:ConStruct 1.0: An R Script to distinguish between substructure and consanguinity within a population using multilocus microsatellite data
  • 本地全文:下载
  • 作者:Andrew D.J. Overall
  • 期刊名称:Cogent Biology
  • 电子版ISSN:2331-2025
  • 出版年度:2016
  • 卷号:2
  • 期号:1
  • DOI:10.1080/23312025.2015.1128317
  • 出版社:Taylor and Francis Ltd
  • 摘要:

    ConStruct.1.r is an R Script that estimates the relative contributions of consanguinity and population substructure to excess homozygosity. ConStruct.1.r also offers the option of simulating data with a given and magnitude of consanguinity, incorporating a user-specified number of loci, number of alleles and population size. The method seems robust when population sizes are above 200 and individuals are genotyped at greater than 10 loci.

  • 关键词:R Script ; consanguinity ; population substructure ; microsatellites ; FST
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