As the greatest production tool in twenty-first Century, computer technology has the non-substitute status in people's life. With the expansion of the Internet, the computer has a profound impact on modern life. Human resources management department actively introduce computer technology, to provide technical support for social security work. The wide application of computer in human resource management has greatly promoted the development of social security Since the reform and opening up, China has introduced the market competition system, greatly liberated and developed the productive forces.. With the development of social economy and technology, computer application technology has penetrated into every field of the society, which greatly facilitates people's production and life.. Government departments also actively use computer network system. This paper mainly talks about the application of computer in human resources and social security, and studies the effective way to improve the work efficiency of human resource and social security department.