Purpose: Explore the parameters of excellent athletes’ body immune status for various sports and better understand athlete’s immune function status, thus providing guidance for athlete’s daily training, adjusting exercise load timely, and adopting scientific exercise methods to improve various body functions. Method: Choose 186 athletes from various provinces and cities in China, including basketball players, weight lifters, fencers, track men, modern pentathletes, and military pentathletes. And then comparative analysis should be conducted on 186 athletes and 173 control personnel from physical examination center. Determine the T, B and NK lymphocyte subsets and other immune parameters of various athletes, divide the athletes into groups based on their sports events, take them as the experimental group, and then compare them with the control group. Result: Comparing the immune indexes of various athletes with that of the normal people, it can be found that the indexes of T suppression lymphocyte (CD3+CD8+) and NK lymphocyte (CD3-CD56+) are both lower than that of the control group (P<0.05), while the body immune function status is of no statistical significance (P<0.05). It can be seen by comparing the various athletes’ immune indexes that the CD3+ and CD3+CD4+ indexes of Group 2 and Group 3 are higher than that of Group 1 (P<.05); the CD3-CD56+ index of Group 3 is lower than that of Group 1 (P<0.05); the CD3-CD19+ index of Group 1 and Group 3 is lower than that of Group 2 (P<0.05). Conclusion: Various athletes have different immune indexes, Compared with the normal people, athletes have lower basic immune parameters of T, B and NK lymphocyte.