Aim at the reservoir characteristics of Suizhong 36-1 Oil Field, this paper has developed typical two-dimensional physical model in parallel between the layers and studied the macroscopic displacement effect of polymer flooding and binary compound flooding, and studied the interlayer spread law and oil displacement efficiency of polymer flooding and binary combination flooding by using saturation monitoring system deeply. The results show that: when the multiples of pore volume injected for polymer was 0.3 after water flooding, the recovery efficiency increased by 10.3%, and when the multiples of pore volume injected for binary combination flooding was 0.3 after polymer flooding and the recovery efficiency could also increase by 19.3%, and the effect of enhanced oil recovery was obvious during the binary combination flooding and polymer flooding; Saturation monitoring data showed that there formed oil wall and increased the flow resistance and expanded the swept volume during the stage of polymer flooding and binary combination flooding, effective use of low-permeability layer was the key to improve oil recovery.