摘要：BACKGROUND: Even today physical activity is not considered as a real treatment for diabetes but the literature suggests that regular physical activity is of great importance in the management of type 1 diabetes mellitus. Moreover a regular physical activity has been associated with weight control, improved blood lipid profile, reduced cardiovascular risk and improved sense of well being. Several studies have suggested that elevated levels of glycated hemoglobin (HBA1C) are associated with cardiovascular disease (CVD); the objective of the present pilot was to evaluate the relationship between HBA1C levels and physical activity. METHODS: The subjects were recruited during regularly scheduled clinic visits. Seventeen youths (12 girls and 5 boys) with type 1 diabetes and disease duration of at least 24 months and were recruited from a university-based outpatient diabetes specialty clinic, without any other known disease. We required the dosage HBA1C to patients that, subsequently, came to their regular outpatient visit having the HBA1C test. Moreover, we administered a short questionnaire in order to evaluate the total physical activity time carried out in one week. RESULTS: Seventeen subjects were enrolled in this study (age: 14,43 ± 2,83 yrs; weight: 58,79 ± 15,68 kg; height: 159,91 ± 12,99 cm; BMI: 22,72 ± 4,78). Through the Pearson correlation index, the data analysis demonstrated that HBA1C levels (9.98 ± 2.18 %) exhibited a significant reverse correlation (r = - 60) with total physical activity time carried in one week (432, 05 ± 214,58 min). CONCLUSIONS: In conclusion, our data support the hypothesis that regular exercise can improve longterm glucose control, according to HBA1C levels and ultimately, improve metabolic control in subjects with type-1 diabetes. If confirmed by future studies, our findings propose physical activity as a accompanying treatment for type 1 diabetes. Larger numbers are necessary to confirm these hypothesis but these results are very encouraging.
关键词：Physical activity; Adolescents; Glycated hemoglobin; Type 1 Diabetes Mellitus.
