Manufacturing industry includes all processes related to the manufacturing of raw materials and /or some components and has 24 sub-sectors. In this paper, the goal of the research is the analysis of large manufacturing companies active in Romania, ie those companies that have a number of workers between 250 and 999 employees, in terms of economic and financial performance in 2008-2013 . For this purpose we analyzed operating income, profit / loss and operating margin to evaluate financial performance, and the evolution of exports and imports, gross added value and the number of workers to assess economic performances.