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文章基本信息

  • 标题:Efficacy and Safety of Different Antimycotic Formulas Used in Sheep Frozen Semen Extenders
  • 本地全文:下载
  • 作者:Fadwa M. Othman ; Diya A. El-Badry ; Mahmoud I. Mohamed
  • 期刊名称:Alexandria Journal of Veterinary Sciences
  • 印刷版ISSN:1110-2047
  • 电子版ISSN:1110-2047
  • 出版年度:2016
  • 卷号:48
  • 期号:2
  • 页码:77-82
  • DOI:10.5455/ajvs.202266
  • 出版社:International Medical Journal Management and Indexing System
  • 摘要:This study aimed to select a potent and safe antimycotic as additive to cryodiluents of sheep frozen semen. Semen samples were collected from 6 Barki rams and processed for cryopreservation after adding different concentrations of griseovulvin, clotrimazole, nystatin, fluconazole or amphotricin-B to semen diluent. Sensitivity of Candida albicans and Cryptococcus neoformans to antimycotic drugs were studied. Results showed that fluconazole and nystatin (at dose not higher than 50 mg/L) had no deleterious effect on sheep semen freezability. Higher doses of amphotricin-B and griseofulvin resulted in drastic deterioration of frozen semen quality. Candida albicans and Cryptococcus neoformans were sensitive to fluconazole and amphotricin-B and resistant to lower concentrations of griseovulvin and clotrimazole. Conclusively, addition of fluconazole to sheep semen diluent has a benefit of improving the quality of yeast contaminated sperm with no bad effect on the frozen-thawed semen quality.
  • 关键词:anti-mycotic; griseovulvin; clotrimazole; nystatin; fluconazole; amphotricin-B; Candida; Cryptococcus; frozen semen; sheep
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