42-year-old woman who had suffered cardiac arrest because of hypovolemic shock was intractable to conventional cardiopulmonary resuscitation (CPR). After 34 minutes of CPR, we decided to start extracorporeal membrane oxygenator (ECMO) in order to provide adequate cerebral and coronary perfusion. She received hysterectomy and bleeding control for 2 hours 30 minutes, and three hours after the operation, she weaned from the 362 minutes ECMO support successfully and was extubated 12 hours after ECMO weaning on postoperative 1st day. She revealed no neurologic deficit on neurologic examination and electroencephalography. Her cardiac function was decreased when the initial ECMO support was started, but improved into normal status. She suffered from skin burn on defibrillation site, generalized myalgia, and ileus, but was discharged from the hospital without major complications on postoperative 17th day. Extracorporeal cardiopulmonary resuscitation (ECPR) in patients who did not respond conventional CPR can be a feasible option in selected patients.