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  • 标题:The Trial of Continuous Intravenous Infusion of Magnesium in Patients with Postherpetic Neuralgia Refractory in Conventional Treatment: A report of 2 cases
  • 本地全文:下载
  • 作者:Cheong, Yong Kwan ; Kim, Tai Yo ; Lee, Ju Hwan
  • 期刊名称:Korean Journal of Anesthesiology
  • 印刷版ISSN:2005-6419
  • 出版年度:2006
  • 卷号:50
  • 期号:3
  • 页码:361-364
  • DOI:10.4097/kjae.2006.50.3.361
  • 语种:English
  • 出版社:The Korean Society of Anesthesiologists,
  • 摘要:

    Postherpetic neuralgia is one of the most troublesome diseases in pain clinics. The N-methyl-D-aspartate (NMDA) receptor antagonist, magnesium, reduces the level of neuropathic pain and hyperalgesia in patients with postherpetic neuralgia. Magnesium has been shown to exert a physiological block of the ion channel on the NMDA receptor, thereby preventing extracellular calcium ions from entering the cell and contributing to secondary neuronal changes. Accordingly, we attempted to administer a continuous intravenous infusion of magnesium, which resulted in a decrease in the VAS without side effects.

  • 关键词:magnesium; Neuropathic pain; NMDA receptor antagonist; postherpetic neuralgia
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