We present a case of a patient who had undergone human allograft cardiac transplantation 5 months before ascending aorta replacement. A pseudoaneurysm at the anastomotic site of ascending aorta with periaortic hematoma compressing the superior vena cava (SVC) had been revealed by chest CT, and after the median sternotomy, paraaortic abscess was revealed as the cause of this patient's SVC syndrome. The ascending aorta replacement was performed under deep hypothermic circulatory arrest. The anesthetic management of this patient included the use of a sterile technique, slow cautious induction, and the maintenance of adequate intravascular volume.