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  • 标题:Does Methergine Aggravate Chest Symptom and/or Electrocardiographic Changes during Cesarean Delivery under Spinal Anesthesia?
  • 本地全文:下载
  • 作者:Hong, Jeong Yeon ; Oh, Jong In
  • 期刊名称:Korean Journal of Anesthesiology
  • 印刷版ISSN:2005-6419
  • 出版年度:2005
  • 卷号:48
  • 期号:6
  • 页码:S15-S20
  • DOI:10.4097/kjae.2005.48.6.S15
  • 语种:English
  • 出版社:The Korean Society of Anesthesiologists,
  • 摘要:Background

    Complaints of chest symptoms including pressure, tightness, or pain frequently occur during cesarean delivery under regional anesthesia. The aim of this study was to test whether methergine (methylergonovine maleate) aggravates chest symptoms and/or ECG changes during cesarean section under spinal anesthesia, and to determine if these changes are associated with any discernable intraoperative event.

    Methods

    After delivery, patients were given intravenous methergine 0.2 mg and diluted oxytocin 10 i.u. in 1000 ml Ringer's lactate solution (Methergine group, n = 30) or diluted oxytocin 20 i.u. (Control group, n = 29). ECG and hemodynamic responses were monitored continuously on 12 leads perioperatively.

    Results

    Methergine significantly increased the incidence of chest symptoms compared to the control group (30% vs. 3.4%, P < 0.05), but this increase was not correlated with ECG ST segment changes or with other intraoperative events. ECG changes suggestive of myocardial ischemia occurred in the two groups to similar extents (34.5% vs. 30%, P > 0.05).

    Conclusions

    Methergine-induced chest symptoms per se do not signify evident myocardial ischemia during cesarean delivery. However, anesthesiologists must not overlook the possibility of a small coronary arteriolar spasm, especially in high-risk patients.

  • 关键词:cesarean section; Electrocardiogram; methylergonovine maleate; myocardial ischemia; spinal anesthesia
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