Natural rubber latex is a processed plant product that is manufactured from the rubber tree, Hevea braziliensis. Allergy to natural rubber latex, which contains a complex blend of water-soluble plant proteins, is a major source of concern in clinical practice. Latex is the inciting factor in at least 10 percent of anaphylactic reactions that have been reported during anesthesia. IgE-mediated sensitization to natural rubber latex could induce hypersensitivity reactions ranging from mild contact urticaria to potentially life-threatening anaphylaxis. Because of the ubiquitous use of latex in medical equipment and devices, anesthesiologist should give more attention and to the management of the allergic reactions to latex in high risk groups. We report upon the anesthetic management of a parturient undergoing Cesarean section, in which an allergic reaction to latex developed just after the insertion of latex urethral catheter.