Postoperative neurological deficits are uncommon and may arise from diverse causes, and persistent neurological complications resulting from epidural anesthesia are extremely rare. We experienced a case of unilateral lower limb paralysis in a patient after abdominal hysterectomy under general and epidural analgesia. The condition persisted for more than several weeks despite gradual improvement, and believed to have resulted from epidural analgesia. However, neurological examination, electromyography (EMG) and nerve conduction study (NCS) revealed isolated peripheral femoral neuropathy rather than radiculopathy. This neurological deficit seemed to have been caused by the self-retaining retractor, used intraoperatively. If the cause of a neurological complication is peripheral neuropathy, then it is probably associated with the surgical procedure rather than the anesthetic procedure.