期刊名称：Iranian Journal of Psychiatry and Clinical Psychology
印刷版ISSN：1735-4315
电子版ISSN：2228-7515
出版年度：2009
卷号：15
期号：2
页码：168-174
语种：English
出版社：Tehran University of Medical Sciences
其他摘要：Abstract Objectives : The aim of this study was to evaluate the outcome of a group of patients with bipolar I disorder admitted to Roozbeh Hospital, Tehran, Iran, during one year follow up. Method : In this prospective naturalistic study, 131 subjects with bipolar I disorder who were con-secutively admitted to the hospital were enrolled. Patients were assessed at baseline, discharge, and 6 and 12 months after admission to the hospital. Different aspects of response to treatment including severity of mood and psychotic symptoms, extrapyramidal side effects, global functioning and service satisfaction were assessed using a demographic questionnaire, Young Mania Rating Scale (Y-MRS), and Hamilton Rating Scale for Depression (HAM-D). Results : Severity of symptoms and function showed significant improvement only at discharge (p and was not significant afterwards. Patients showed a response rate of 65.4% based on 50% decrease on (Y-MRS), at discharge. Conclusion : Improvement in symptom severity and global functioning was significant at discharge but there was no significant improvement after discharge and during one year follow up.
关键词：اختلال دوقطبی؛ پیامد درمان؛ بررسی طولی
其他关键词：bipolar disorder; treatment outcome; longitudinal study
