标题：PHARMACOLOGICAL INTEGRATION: ADJUNCT EFFECT OF DB14201, A NEW HERBAL FORMULATION DEVELOPED BASED ON AYURVEDIC PRINCIPLES, WHEN CO-ADMINISTERED WITH GLIBENCLAMIDE: RESULTS OF A PLACEBO CONTROLLED TRIAL
期刊名称：Annals of Geriatric Education and Medical Sciences
印刷版ISSN：2348-7348
电子版ISSN：2348-7240
出版年度：2015
卷号：2
期号：1
页码：2-10
语种：English
出版社：Innovative Publication
摘要：There exist many therapeutic windows in the clinical area of Type 2 Diabetes. Traditional Medicines, including Ayurveda should be explored to identify safe and effective medicines for diabetes. DB14201 is an herbal formulation from Ayurvedic traditional knowledge and has been safely used by diabetics as a supplement drink for several years. Diabetics on hypoglycemic agents soon outgrow the effectiveness of an oral hypoglycemic agent and needs to add more of the same medicine or medicines with different mechanisms of action or insulin. A safe herbal add-on to oral hypoglycemics which can improve the efficacy of glycemic control and offer longer window of time for a specific dosage would greatly improve the current management of diabetes. The current study proves that DB14201 when used with glibenclamide as an add-on improves its efficacy in glycemic control as evidenced by comparatively lower fasting and post prandial blood sugar level in the study group as against the placebo group. The addition of DB14201 also helps in reduction of HbA1c levels by nearly 1% points over a period of 90 days.
