摘要:In Colombia, the cigarette smoking varies according to the region. However, variables associated with daily cigarette smoking are unknown almost all of these cities. The objective of this research was to establish the prevalence and factors associated with the daily cigarette smoking at the city of Bucaramanga, Colombia. A cross-sectional study was carried out. A multistage and representative sample from the general population was surveyed. Smoker denomination was given to persons who smoke everyday during last-month. The General Health Questionnaire was used in order to identify anxiety and depressive symptoms. A total of 2,496 adults participated in this research, with aged between 18 and 65 years-old (mean 34.5, SD = 12.5), 69.7 % were females, average scholarship was 9,2 years (SD = 4.1), 49.1 % had an employ, 58.1 % were married, and 67.8 % was dwelling in medium socioeconomic status. The prevalence of daily cigarette smoking weighted by gender was 12.5 % (95 % CI 11.2-13.8). The daily cigarette smoking was associated with being a male (OR = 3.2; 95 % CI 2.3-4.4), alcohol abusive consumption (OR = 3.2; 95 % CI 1.9-5.5), daily caffeine drinking (OR = 2.7; 95 % CI 2.0-3.6), meaningful clinically anxiety and depressise symptoms (OR = 2.6; 95 % CI 1.8-3.7), less education (0-5 years compared with 6-11 years, OR = 0.84; 95 % CI 0.61-1.2; and 12 o more OR = 0.52; 95%CI 0.33-0.81), and being a single person (OR = 1.6; 95 % CI 1.2-2.2). As conclusion, almost 12.5 percent of urban adults of Bucaramanga, Colombia, are daily cigarette smokers. It is very important to promote smoking cessation in this population. Keywords: Smoking, epidemiology, prevalence, general population, adults, cross-sectional study