摘要：The purpose of this study was to determine whether quadriceps strength and whole muscle volume or distal vastii muscle volumes (Vastus Medialis: VM, Vastus Lateralis: VL) are associated with Magnetic Resonance Imaging (MRI)-derived measures of patellar cartilage morphology in patients with knee Osteoarthritis (OA). Twenty (13 female) community dwelling participants with knee OA completed isometric maximal voluntary knee extensor contractions for determination of maximal torque. MRI using 3D multi-echo spoiled gradient echo imaging sequences and a multi-point fat-water separation method were used to acquire images of the quadriceps and the PF joint. The determinants of cartilage volume, mean cartilage thickness and maximum cartilage thickness were obtained from stepwise multiple linear regression models. A stepwise model including distal VM volume (β = 0.54) and isometric torque (β = 0.40) predicted the greatest proportion of variance in cartilage volume (adjusted r2 = 0.75, p
