摘要:Figures Authors K. Aoun 12 * G. Halima 3 T. Ahmed 1 N. Ben Alaya 4 I. Ben Sghaier 1 B. Nadia 1 C. Hanene 1 M. Ben Abid 1 Z. Harrat 5 M. Raouane 2 A. Bouratbine 16 1 LR 11-IPT-06 Parasitoses médicales, biotechnologie et biomolécules, Tunisie 2 Laboratoire d’épidémiologie et d’écologie parasitaires, Institut Pasteur de Tunis, Tunisie 3 Direction régionale de la santé, Tataouine, Tunisie 4 Observatoire national des maladies nouvelles et émergentes 5 Institut Pasteur d’Algérie 6 Laboratoire de parasitologie-mycologie, Institut Pasteur de Tunis, Tunisie * Correspondance Key words: Cutaneous leishmaniasis, epidemic, Leishmania major, Ksar Ouled Dabbab, Tunisia DOI : 10.1684/mst.2015.0468 Page(s) : 39-44 Published in: 2016 Zoonotic cutaneous leishmaniasis (ZCL), due to Leishmania major, and chronic CL, due to L. tropica, are endemic in the governorate (administrative subdivision) of Tataouine (southeast Tunisia). This study aims to analyze epidemiologic, clinical, parasitologic, and entomologic data collected during the 2012-2013 epidemic in Ksar Ouled Dabbab (KOD). Methods: The KOD health care center diagnosed 164 CL cases from July 2012 to March 2013, identifying 21 Leishmania isolates and local sandflies. Results: The incidence rate of CL in KOD was around 27.5/1000 inhabitants. The age groups most strongly affected were children younger than 10 years (19.9%) and those aged 10-20 years (23.1%). The number of patients with multiple lesions (67.9%) and their location on limbs (71.3%) indicated ZCL. This hypothesis is supported by the high proportions of L. major (81%) and Phlebotomus papatasi found. Conclusion: The epidemiologic and clinical profiles of the cases and the predominance of L. major and P. papatasi confirm that the recent outbreak in KOD was related to ZCL. It probably followed recent environmental changes and transmission spread from adjacent neighboring foci.