标题：Evaluation of the efficacy and safety of three 2-drug combinations for the treatment of uncomplicated Plasmodium falciparum malaria in Senegal: artesunate-amodiaquine, dihydroartemisinin-piperaquine, and artemether-lumefantrine
摘要：Figures Tables Authors D. Sow 1 * J.-L. Ndiaye 1 K. Sylla 1 M.S. Ba 1 R.C.K. Tine 1 B. Faye 1 M. Pene 1 M. Ndiaye 1 A. Seck 2 A.C. Lo 1 A. Abiola 1 Y. Dieng 1 O. Gaye 1 1 Service de parasitologie, faculté de médecine, université Cheikh Anta Diop, Fann, 5005 Dakar, Sénégal 2 Worldwide Antimalarial Resistance Network (WWARN), Sénégal * Correspondance Key words: uncomplicated malaria, artemether-lumefantrine, artesunate-amodiaquine, dihydroartemisinin-piperaquine, efficacy, Plasmodium falciparum, Senegal DOI : 10.1684/mst.2015.0524 Page(s) : 45-50 Published in: 2016 Background Since 2006, artemisinin-based combination therapies (ACT) have been used to treat uncomplicated Plasmodium falciparum malaria in Senegal, as recommended by WHO. Recently, decreased parasite clearance with artemisinin derivatives has been reported in Cambodia and Thailand. The effectiveness of artemisinin derivatives in Africa must be monitored. This study was conducted to evaluate the efficacy and the tolerability of three ACT widely used in Senegal.
