期刊名称:Studia Universitatis Moldaviae: Stiinte Sociale
印刷版ISSN:1814-3199
电子版ISSN:2345-1017
出版年度:2014
卷号:6
期号:76
页码:119-123
出版社:Moldova State University
摘要:The paper presents the synthesis of the ligand 5-nitrofuran-2-carbaldehyde N(4)-allyl-3-thiosemicarbazone (HL) and eight coordination compounds of copper(II) and nickel(II) with this ligand. The structure of thiosemicarbazone HL was studied using 1 H and 13 С NMR spectroscopy. For the synthesized compounds their antimicrobial and antifungal activity was studied on a series of standard strains. For HL and Cu(HL) 2 (NO 3 ) 2 the antitumor activity towards human leukemia HL-60 cells was estimated. It was established that coordination compounds manifest better activity than free ligand