摘要:The nature freely offers us many resources for health and beauty. The ferns and their therapeutic properties are less exploit in Romania, except Lycopodium clavatum and Equisetum arvense. Some of the fern properties were demonstrated, like antioxidant, antimicrobial, antiviral, antihelmintic properties. Plants are reasonable alternative to synthetic drugs, avoid the side effect and high cost of synthetic drugs production. Also, the drug resistance bacteria can be controlled using plant derived remedies. In this study the antimicrobial effect of methanolic and ethanolic extracts from three fern species were tested. The extracts were gained from gametophytic stage of ferns obtained in vitro. The most obvious effect was observed for Asplenium trichomanes-ramosum extract. The total polyphenols and flavonoids content were established, too